ONE BIOSCIENCES – Molecular Biology Lab Technician

Molecular Biology Lab Technician
Full time employee position
Location: Paris (offices in Biolabs, 75014)
About One Biosciences: One Biosciences is a pioneering precision diagnostics company
uniquely positioned to decipher tumor heterogeneity through the convergence of single-cell
transcriptomics and artificial intelligence. Our proprietary platform combines cutting-edge
biological protocols, advanced algorithms, and molecular signatures to deliver clinical-grade

insights that transform cancer treatment decisions. Leveraging proprietary and public single-
cell datasets in oncology, our technology enables healthcare providers to understand the

complex cellular landscape of tumors with unprecedented precision and speed. We have
established strategic partnerships with leading French cancer centers including Institut Curie
and Gustave Roussy, while preparing an expansion in the US market through collaborations
with top-tier institutions. Following our successful €14M Series A funding round led by
prominent investors, One Biosciences is scaling globally to bring the next generation of
precision diagnostics to oncologists and pharmaceutical companies worldwide. Join us in our
mission to revolutionize cancer care by unlocking the secrets hidden within every single cell.
The Context:
As we scale our operations globally and expand our partnerships from Europe to the US, we
are entering a critical phase where we need to increase our capabilities in terms of output in
the wetlab to manage more and larger projects.
As part of this strategic evolution, the lab technician will be responsible to work in the lab to
process samples from raw material to sequencing.
Your missions
Your daily task will be to generate single-cell data from FFPE samples under the supervision of
a laboratory engineer. You should be comfortable with routine laboratory work.
• Carry out and ensure the completion of single cell omics data generation pipelines in
a standardized fashion way:
o Organize human sample reception (Frozen and/or FFPE)
o Perform librairies preparation (10X genomics)
o Implement PCR/qPCR techniques, purification, dosage and quality control
o Prepare and launch sequencing runs (NGS-Illumina)
o Report results autonomously and clearly (Labguru)
• Assist the research team in development and validation of new multi-omics
experiments.
• Assist in monitoring stocks, orders and equipment maintenance.

Education level
• BTS or DUT/BUT (Bioanalyses; Biotechnologies; Biological engineering or related
disciplines).
• At least two-years of proven experience in Molecular Biology.
• Experience on a genomics and/or sequencing platform.
Must-have experience and skills
• Working on human sample (dissociation/extraction of cells or nuclei) and using
microscopy (fluorescence).
• Molecular biology: library preparation for NGS, bioanalyzer or Tapestation, DNA and
RNA extraction, qPCR, RT-PCR.
• Experience in single-cell experiments (10X for instance) and robot dispensers
(EpiMotion, Mosquito …) would be be particularly appreciated.
• Familiarity with quality standards (ISO 15189, ISO 17025, GLP, etc.) would be be
particularly appreciated.
Non technical skills
• Comfortable with routine laboratory work
• Good level in English (reading, writing and speaking);
• Excellent communications and team working skills;
• Rigorous; high standards of integrity, accuracy and attention to details;
• Adaptable, organized, rigorous and results-oriented.
• Strong team spirit, taking initiatives to help out others when needed.

Veuillez postuler directement en vous adressant au contact indiqué dans l’offre ci-avant. L’ESTBA ne traitera aucune candidature. Merci.